The PennZone

Single ~ CS Genetics, a leading company in next-generation single-cell genomics, has announced the launch of their latest product, the SimpleCell™ 3' Gene Expression kits. This is the company's first commercial offering and is designed to make single-cell transcriptomics more accessible and scalable.

The SimpleCell™ platform utilizes Kinetic Confinement, a revolutionary molecular process, to provide an instrument-free and scalable solution for single-cell genomics. This technology has been in development for several years and is now being released commercially.

Luke Edelman, Founder and Chief Technology Officer at CS Genetics, expressed his excitement about the launch of SimpleCell™. He stated, "After several years of development, we are so excited to be releasing our first SimpleCell™ products commercially. Single cell is a very important and impactful modality for biological measurement, and we feel strongly that a diverse ecosystem of technology platforms – now including Kinetic Confinement and SimpleCell™ – is good for the field and for the cadence of discovery."

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The SimpleCell™ 3' Gene Expression kits have several key features that make them stand out in the market. These include a single-day cells-to-sequencer workflow using standard lab equipment and pipetting, cost-effectiveness at under $500 per sample regardless of experiment scale or purchase volume, and compatibility with various sample types such as blood/PBMCs, cell lines, disaggregated solid tissues, and more.

CS Genetics will be showcasing details about Kinetic Confinement technology and the SimpleCell™ product line at the 2024 Annual Meeting of the American Society for Human Genetics in Denver. Attendees can visit CS Genetics at booth 402 or join the SimpleCell™ CoLab talk on Wednesday, November 6th at 4:00 PM in Theater 3 to learn more about the future of single-cell genomics.

Early customers of SimpleCell™ have already expressed their satisfaction with the product. Charlly Kao, Principal Scientist at the Center for Applied Genomics (CAG) at the Children's Hospital of Philadelphia, shared, "We've been eagerly waiting for something like SimpleCell™ that can perform single-cell transcriptome profiling in a flexible, instrument-free, and simple-to-use workflow at a more attractive price point."

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Hákon Hákonarson, Director of the Center for Applied Genomics at the Children's Hospital of Philadelphia and Professor of Pediatrics at the Perelman School of Medicine, also commented on the potential impact of SimpleCell™. He said, "Kinetic Confinement and the SimpleCell™ platform are timely new additions to the single cell universe. As a translational research facility with access to a very large number of clinical specimens, we are particularly excited about the opportunities presented by the platform to enable significantly larger-scale single cell studies than has been realistically possible with other tools."

Yuriy Alekseyev, director of the Single Cell and NGS core laboratory at Boston University Chobanian & Avedisian School of Medicine, also praised SimpleCell™ for its affordability and ease-of-use. He stated, "SimpleCell™ checks these boxes well. It's simple to set up, cost-effective, and a welcome addition for users who've been looking for a platform that doesn't require a huge learning curve or large costs for each experiment."

The SimpleCell™ 3' Gene Expression kits are available in 8-sample and 16-sample sizes and can now be ordered for shipment across the U.S., U.K., Europe, and select global regions through CS Genetics' website. To learn more about this innovative product or to place an order, visit www.csgenetics.com.

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